Signs and Symptoms of Multiple Myeloma
Multiple Myeloma : Signs And Symptoms Multiple myeloma is a form of cancer in the bone marrow, mainly manifested by the rapid and uncontrollable multiplication of its cells. The signs and symptoms associated with Multiple Myeloma are as follows: Bone pain and breaks The most common symptom of multiple myeloma is bone pain and it usually involves your back and ribs. Unlike other forms of cancer which could afflict you, the pain in myeloma is suddenly caused and provoked by your movements. If ever there is a persistent pain in a certain site of your body, it could mean that a bone fracture has taken place, which is one of the unfortunate consequences of your disease. Normally, you have two kinds of bone cells that harmoniously work together. These are the osteoclasts and the osteoblasts. The osteoclasts destroy old bones, while the osteoblasts build new ones. When you have multiple myeloma, a certain substance is produced wherein the osteoclasts are given signals to keep on destroying bones. However, the osteoblasts do not receive any kind of signals that they will construct new ones. With this discrepancy, more bones are destroyed rather than constructed. Thus, you have bone destructions if you have the disease.