Canines suffer from various kinds of poisoning. Based on what kind of toxic they are exposed to, the general signs of poisoning include vomiting, diarrhea, seizures, blood in stool, lethargy, loss of appetite, bruising, nosebleeds, inability to urinate, irregular heartbeat. Following are the signs of poisoning in canines that you need to look out for: Drooling It is a typical sign of nausea in canines. If the dog is drooling excessively, then it might be experiencing poisoning. Excessive foaming may lead to foaming in the mouth. Loss of appetite The first sign of illness in any canine is change in eating habits. If the dogs skips meals frequently and shows other symptoms of poisoning, then it is needs to be taken to a vet immediately. Loss of coordination This is an indication that the brain is affected by an ingested toxin. The dog might have trouble walking, and might appear dizzy. Xylitol which is found in peanut butter leads to lack of coordination in some canines. Here are signs of poisoning based on various types of factors: Neurological poisoning symptoms Neurological and seizure poisoning is caused due to several kinds of factor strychnine, tobacco, asprin, antidepressants , alcohol, marijuana, flea repellents, drain cleaners, dishwasher detergent.